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Asger Granfeldt Selected Research

senicapoc

1/2022Senicapoc treatment in COVID-19 patients with severe respiratory insufficiency-A randomized, open-label, phase II trial.
1/2022Treatment with senicapoc, a KCa 3.1 channel blocker, alleviates hypoxaemia in a mouse model of acute respiratory distress syndrome.
6/2021Effect of the KCa3.1 blocker, senicapoc, on cerebral edema and cardiovascular function after cardiac arrest - A randomized experimental rat study.
4/2021Treatment with senicapoc in a porcine model of acute respiratory distress syndrome.

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Asger Granfeldt Research Topics

Disease

36Heart Arrest (Cardiac Arrest)
01/2022 - 08/2012
7Out-of-Hospital Cardiac Arrest
01/2022 - 11/2017
6Pulmonary Embolism
11/2020 - 07/2017
6Hemorrhagic Shock
12/2019 - 08/2012
4Hemorrhage
12/2021 - 11/2012
3Necrosis
01/2022 - 11/2009
3Myocardial Infarction
12/2021 - 08/2012
3Hypoxia (Hypoxemia)
01/2020 - 07/2017
3Critical Illness (Critically Ill)
01/2020 - 11/2009
3Chronic Disease (Chronic Diseases)
01/2018 - 11/2016
3Ventricular Fibrillation
09/2017 - 11/2013
3Inflammation (Inflammations)
08/2014 - 05/2008
2Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome)
01/2022 - 04/2021
2Disseminated Intravascular Coagulation
01/2022 - 12/2021
2Pulmonary Edema
01/2022 - 07/2009
2Lung Injury
01/2022 - 04/2021
2Infarction (Infarctions)
12/2021 - 01/2021
2Sepsis (Septicemia)
12/2021 - 01/2020
2Syncope (Fainting)
12/2019 - 12/2019
2Hypotension (Low Blood Pressure)
12/2019 - 12/2014
2Wounds and Injuries (Trauma)
01/2019 - 12/2016
2Asphyxia (Suffocation)
08/2018 - 01/2017
2Chronic Obstructive Pulmonary Disease (COPD)
01/2018 - 11/2016
2Reperfusion Injury
11/2017 - 03/2011
2Cardiac Arrhythmias (Arrythmia)
09/2017 - 07/2017
1Pulmonary Atelectasis
11/2022
1Ventilator-Induced Lung Injury
01/2022
1Anastomotic Leak
01/2022
1Coma (Comas)
01/2022
1COVID-19
01/2022
1Brain Diseases (Brain Disorder)
01/2022
1Surgical Wound Infection
01/2022
1Respiratory Insufficiency (Respiratory Failure)
01/2022
1Hypercalcemia (Milk Alkali Syndrome)
12/2021
1Coronary Occlusion
12/2021
1Brain Edema (Cerebral Edema)
06/2021
1Hyperoxia
01/2019
1Heart Diseases (Heart Disease)
06/2018
1Hyperkalemia
09/2017
1Hypovolemia
09/2017

Drug/Important Bio-Agent (IBA)

5Vasopressins (Vasopressin)IBA
01/2022 - 03/2021
5CalciumIBA
01/2022 - 01/2020
5Lidocaine (Xylocaine)FDA LinkGeneric
01/2020 - 11/2012
5Adenosine (Adenocard)FDA LinkGeneric
01/2020 - 11/2012
5Oxygen (Dioxygen)IBA
01/2020 - 07/2009
4MethylprednisoloneFDA LinkGeneric
01/2022 - 03/2021
4senicapocIBA
01/2022 - 04/2021
4salicylhydroxamic acid (SHAM)IBA
12/2021 - 11/2012
4Anti-Bacterial Agents (Antibiotics)IBA
11/2020 - 11/2016
3CytokinesIBA
01/2022 - 05/2008
3PotassiumIBA
01/2022 - 01/2017
3Pharmaceutical PreparationsIBA
11/2020 - 09/2020
3Adrenal Cortex Hormones (Corticosteroids)IBA
01/2020 - 11/2016
3adenocaineIBA
11/2013 - 08/2012
2Epinephrine (Adrenaline)FDA LinkGeneric
01/2022 - 10/2018
2Proteins (Proteins, Gene)FDA Link
01/2022 - 04/2021
2Dacarbazine (DIC)FDA LinkGeneric
01/2022 - 12/2021
2AlbuminsIBA
04/2021 - 11/2009
2MagnesiumIBA
01/2020 - 01/2020
2GasesIBA
01/2019 - 11/2009
2CI 22IBA
09/2017 - 07/2017
2Superoxides (Superoxide)IBA
11/2013 - 08/2012
1GlucocorticoidsIBA
01/2022
1Troponin IIBA
12/2021
1AntithrombinsIBA
12/2021
1BradykininIBA
10/2021
1Calcium-Activated Potassium Channels (Calcium-Activated Potassium Channel)IBA
10/2021
1Nitroprusside (Sodium Nitroprusside)FDA LinkGeneric
10/2021
1Phosphopyruvate Hydratase (Enolase)IBA
10/2021
1Interleukin-6 (Interleukin 6)IBA
04/2021
1triphenyltetrazoliumIBA
01/2021
1Evans Blue (Blue, Evans)FDA Link
01/2021
1Bicarbonates (Hydrogen Carbonate)IBA
01/2020
1Lactic Acid (Lactate)FDA LinkGeneric
01/2020
1Glycerol (Glycerine)FDA LinkGeneric
01/2020
1pro-brain natriuretic peptide (1-76)IBA
06/2018
1Neuroprotective AgentsIBA
11/2017
1fluanisoneIBA
11/2017
1Anesthetics (Anesthetic Agents)IBA
11/2017
1Midazolam (Versed)FDA LinkGeneric
11/2017
1IsofluraneFDA LinkGeneric
11/2017
1Fentanyl (Sublimaze)FDA LinkGeneric
11/2017

Therapy/Procedure

25Resuscitation
01/2022 - 08/2012
8Therapeutics
01/2022 - 11/2009
8Cardiopulmonary Resuscitation (CPR)
01/2021 - 08/2012
7Induced Hypothermia
01/2022 - 03/2019
4Critical Care (Surgical Intensive Care)
12/2021 - 12/2016
3Drug Prescriptions
01/2018 - 11/2016
2First Aid (Aids, First)
12/2019 - 12/2019
2Defibrillators (Defibrillator)
01/2019 - 01/2018
2Airway Management
01/2019 - 01/2018
2Induced Heart Arrest (Cardioplegia)
08/2018 - 07/2017
1Artificial Respiration (Mechanical Ventilation)
11/2022
1Length of Stay
01/2022
1General Anesthesia
01/2022
1Intravenous Administration
01/2022
1Rewarming
12/2021
1Percutaneous Coronary Intervention
01/2018
1Coronary Artery Bypass (Coronary Artery Bypass Surgery)
01/2018
1Anesthesia
11/2017